Homozygous Hypomorphic HNF1A Alleles Are a Novel Cause of Young-Onset Diabetes and Result in Sulfonylurea-Sensitive Diabetes.
Shivani MisraNeelam HassanaliAmanda J BennettAgata JuszczakRichard CaswellKevin ColcloughJonathan ValabhjiSian EllardNicholas S OliverAnna L GloynPublished in: Diabetes care (2020)
Homozygous hypomorphic HNF1A variants are a cause of HNF1A-MODY. We thus expand the allelic spectrum of variants in dominant genes causing diabetes.