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Reverse-engineering growth and form in Heidelberg.

Michael LevinAlfonso Martinez Arias
Published in: Development (Cambridge, England) (2019)
The EMBO-EMBL Symposium 'Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture' was held in Heidelberg, Germany, in March 2019, with 150 participants seeking to reverse-engineer embryogenesis, emphasizing quantitative simulation and the use of synthetic systems to test models. This highly dynamic, interdisciplinary mix of quantitative developmental genetics, bioengineering, synthetic biology and artificial life aimed to reveal how evolution exploits physical forces and genetics to implement the cell- and tissue-level decision-making required for complex morphogenesis.
Keyphrases
  • decision making
  • single cell
  • mental health
  • genome wide
  • high resolution
  • physical activity
  • genome wide identification
  • copy number
  • bone marrow
  • transcription factor
  • mesenchymal stem cells