The prognostic strength of serum LDH and serum ferritin in children with neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project.

Veronica MorozDavid MachinBarbara HeroRuth LadensteinFrank BertholdPaige KaoYaa ObengAndrew D J PearsonSusan L Cohn Wendy B London

Published in: Pediatric blood & cancer (2020)

LDH and ferritin are strongly prognostic in NB, overall and within high-risk NB patients treated post-2009 with modern therapy. LDH and ferritin show promise for (a) identifying ultra-high-risk; (b) refining risk stratification; and (c) clinical utility in low-/middle-income countries. Routine collection of LDH and ferritin should be reinitiated for evolving NB risk stratification.

Keyphrases

iron deficiency
young adults
physical activity
quality improvement
mental health
clinical practice
stem cells
machine learning
mesenchymal stem cells