Feasibility of dose-dense cisplatin-based chemotherapy in Japanese children with high-risk hepatoblastoma: Analysis of the JPLT3-H pilot study.

Kenichiro WatanabeMakiko MoriTomoro HishikiAkiko YokoiKohmei IdaMichihiro YanoJunya FujimuraYuki NogamiTomoko IeharaKen HoshinoTakeshi InoueYukichi TanakaOsamu MiyazakiTetsuya TakimotoKenichi YoshimuraEiso Hiyama

Published in: Pediatric blood & cancer (2021)

The toxicity profile of JPLT3-H was comparable to that of SIOPEL-4. Dose-dense cisplatin-based chemotherapy may be feasible among Japanese patients with high-risk hepatoblastoma.

Keyphrases

locally advanced
young adults
oxidative stress
squamous cell carcinoma
radiation therapy