Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model.
Aditya GirishDaShawn A HickmanAnkush BanerjeeNorman LucYifeng MaKenji MiyazawaUjjal D S SekhonMichael SunStephanie HuangAnirban Sen GuptaPublished in: Journal of thrombosis and haemostasis : JTH (2019)
Overall, the studies establish the potential of targeted TXA delivery for safe injury site-selective enhancement and stabilization of hemostatic clots to improve survival in trauma.