TREM-1-dependent M1 macrophage polarization restores intestinal epithelium damaged by DSS-induced colitis by activating IL-22-producing innate lymphoid cells.
Fu-Chen YangPo-Yuan ChiuYun ChenTak W MakNien-Jung ChenPublished in: Journal of biomedical science (2019)
TREM-1 plays a crucial role in regulating IL-22 production by ILC3 through modulating M1-macrophage polarization during DSS-induced acute colitis.