Intracellular bacterial eradication using a novel peptide in vitro.

Wing Nok Isaac NgShanthini KalimuthuCarmen Oi Kwan LawAngeline Hui Cheng LeeTerrence Chi Kong LauYiu Yan LeungGary Shun Pan CheungNeelakantan Prasanna

Published in: International endodontic journal (2023)

The results of this study demonstrated that the conjugation of an AMP OP145 to a cell-penetrating peptide R8 eradicated extracellular and intracellular E. faecalis OG1RF without toxic effects on the host cells.

Keyphrases

induced apoptosis
reactive oxygen species
cell cycle arrest
cell therapy
protein kinase
helicobacter pylori infection
cell death
oxidative stress
mesenchymal stem cells
bone marrow
helicobacter pylori