Comparison of 3 Different Prothrombin Complex Concentrate Regimens for Emergent Warfarin Reversal: PCCWaR Study.
Scott K DietrichAnthony Shaun RoweCraig A CocchioAmanda J HarmonSteven F NerenbergPatrick S BlankenshipPublished in: The Annals of pharmacotherapy (2020)
There was no difference in the ability to achieve a post-PCC INR of ≤1.4 between 3 different PCC regimens for warfarin reversal. Additional research is warranted to determine the ideal dose and PCC agent for warfarin reversal.