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Increased investment in gametocytes in asymptomatic Plasmodium falciparum infections in the wet season.

Colins O OdumaSidney OgollaHarrysone AtieliBartholomew N OndigoMing-Chieh LeeAndrew K GithekoArlene E DentJames W KazuraGuiyun YanCristian Koepfli
Published in: BMC infectious diseases (2021)
Parasites increase their investment in transmission in the wet season, reflected by higher gametocyte densities. Despite increased gametocyte densities, parasite density remained similar across seasons and were often below the limit of detection of microscopy or rapid diagnostic test, thus a large proportion of infective infections would escape population screening in the wet season. Seasonal changes of gametocytemia in asymptomatic infections need to be considered when designing malaria control measures.
Keyphrases
  • plasmodium falciparum
  • loop mediated isothermal amplification
  • high resolution
  • label free
  • optical coherence tomography
  • high throughput
  • high speed
  • mass spectrometry