T cell cytokines in the diagnostic of early-onset sepsis.
Glenn Malin FroeschleTanja BedkeMichael BoettcherSamuel HuberDominique SingerChinedu Ulrich EbenebePublished in: Pediatric research (2020)
Interleukin-9 (IL-9) and interleukin-21 (IL-21) are significantly elevated in neonates with early-onset sepsis. IL-9 and IL-21 have been shown to play a specific role in neonatal sepsis. Neonatal reference values were generated for several cytokines. IL-9 and IL-21 might be attractive biomarkers for neonatal sepsis in future. This study is likely to promote further research in this area. Values of several T cell cytokines may be used as reference values for future studies in neonates.