Single-cell transcriptional profiling reveals heterogeneity and developmental trajectories of Ewing sarcoma.

Bo HongYi LiRan YangShuYang DaiYong ZhanWen-Bo ZhangRui Dong

Published in: Journal of cancer research and clinical oncology (2022)

EwS was derived from neural crest cell lineage with variable developmental timing of oncogenic conversion, and the JAK1 might be a candidate for therapeutic targets of EwS.

Keyphrases

single cell
rna seq
transcription factor
high throughput
depressive symptoms
gene expression
oxidative stress
heat shock