Identification of pan-cancer/testis genes and validation of therapeutic targeting in triple-negative breast cancer: Lin28a- and Siglece-based vaccination induces anti-tumor immunity and inhibits metastasis.

Jason A CarterBharati MattaJenna BattagliaCarter SomervilleBenjamin D HarrisMargaret LaPanGurinder S AtwalBetsy J Barnes

Published in: bioRxiv : the preprint server for biology (2023)

Our results present a novel strategy for the identification of highly immunogenic CT antigens for the development of targeted vaccines that induce anti-tumor immunity and inhibit metastasis.

Keyphrases

bioinformatics analysis
cancer therapy
papillary thyroid
computed tomography
dendritic cells
squamous cell
image quality
contrast enhanced
gene expression
squamous cell carcinoma
genome wide
lymph node metastasis
magnetic resonance imaging
young adults
immune response