IRF4 affects the protective effect of regulatory T cells on the pulmonary vasculature of a bronchopulmonary dysplasia mouse model by regulating FOXP3.

Ying ZhuLangyue HeYue ZhuHuici YaoJianfeng JiangHongyan Lu

Published in: Molecular medicine (Cambridge, Mass.) (2024)

IRF4 may affect the protective role of Tregs in the proliferation of pulmonary vascular endothelial cells and pulmonary vascular development in BPD model mice by inhibiting the FOXP3 level.

Keyphrases

regulatory t cells
dendritic cells
pulmonary hypertension
mouse model
endothelial cells
signaling pathway
immune response
type diabetes
adipose tissue
metabolic syndrome
high fat diet induced
skeletal muscle