Is insulin resistance a predictor for complete response in breast cancer patients who underwent neoadjuvant treatment?
Özkan AlanTugba Akin TelliBilge AktasSinan KocaIlker Nihat ÖktenRahib HasanovTugba BasogluRukiye ArikanNazim Can DemircanOzlem ErcelepSerap KayaMustafa Umit UgurluHandan KayaNalan Akgul BabacanFaysal DanePerran Fulden YumukPublished in: World journal of surgical oncology (2020)
Our results revealed that insulin resistance may have a negative effect on pathological complete response (pCR) following neoadjuvant therapy particularly with hormone-positive and Her-2-negative cases of non-diabetic breast cancer.
Keyphrases
- insulin resistance
- rectal cancer
- type diabetes
- locally advanced
- adipose tissue
- lymph node
- high fat diet
- metabolic syndrome
- polycystic ovary syndrome
- skeletal muscle
- high fat diet induced
- squamous cell carcinoma
- stem cells
- wound healing
- single cell
- mesenchymal stem cells
- glycemic control
- young adults
- cell therapy
- breast cancer risk
- childhood cancer