A Comparative Validation of Primary Surgical Versus Post-neo-adjuvant Chemotherapy Sentinel Lymph Node Biopsy for Stage III Breast Cancers.
Gaurav AgarwalSendhil RajanSanjay GambhirPunita LalNarendra KrishnaniSubhash KherukaPublished in: World journal of surgery (2017)
Accuracy of SLNB in T3, N0 tumors undergoing primary surgery is comparable to that of SLNB for N0 EBC. In post-NACT patients, SLNB IR are lower and FNR are higher. Factors predictive of non-identification and false-negative SLNB include pre-NACT skin involvement (T4b), N2a stage or extra-nodal invasion and LVI, and to a lesser extent, young age and UOQ location of the tumor.
Keyphrases
- sentinel lymph node
- end stage renal disease
- lymph node
- neoadjuvant chemotherapy
- ejection fraction
- minimally invasive
- newly diagnosed
- chronic kidney disease
- early stage
- prognostic factors
- peritoneal dialysis
- cell migration
- patient reported outcomes
- squamous cell carcinoma
- ultrasound guided
- soft tissue
- patient reported
- percutaneous coronary intervention
- rectal cancer