Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal.

Parul KudtarkarMaria C CostanzoYing SunDongkeun JangRyan KoestererJosyf C MychaleckyjUma NayakSuna Onengut-GumuscuStephen S RichJason A FlannickKyle J GaultonNoël P Burtt

Published in: PLoS biology (2023)

To address the challenge of translating genetic discoveries for type 1 diabetes (T1D) into mechanistic insight, we have developed the T1D Knowledge Portal (T1DKP), an open-access resource for hypothesis development and target discovery in T1D.

Keyphrases

type diabetes
copy number
healthcare
glycemic control
genome wide
endothelial cells
small molecule
cardiovascular disease
insulin resistance
electronic health record
induced pluripotent stem cells
high throughput
big data
metabolic syndrome
dna methylation
adipose tissue
deep learning
weight loss
single cell