Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells.

Tiejun YangYifeng JingJun DongXinpei YuMingming ZhongLaura E PascalDan WangZhongxian ZhangBaoping QiaoZhou Wang

Published in: The Prostate (2018)

Our findings provide further evidence that ELL2 is a potential tumor suppressor frequently down-regulated in clinical prostate cancer specimens and provides new insights into regulation of ELL2 protein level by polyubiquitination and EAF2 binding.

Keyphrases

prostate cancer
radical prostatectomy
binding protein
transcription factor
fine needle aspiration