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Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation.

Joshua A EnglertMichael H ChoAndrew E LambMaya ShumyatcherDiana Barragan-BradfordMaria C BasilAngelica HigueraColleen IsabelleMayra Pinilla VeraPaul B DieffenbachLaura E FredenburghJoyce B KangAmi S BhattJoseph H AntinVincent T HoRobert J SoifferJudie A HowrylakBlanca E HimesRebecca M Baron
Published in: Respiratory research (2019)
Our findings reveal significant differences in whole blood transcriptomic profiles of patients with non-HSCT ARDS compared to ARDS-HSCT patients and point toward different immune responses underlying ARDS and ARDS-HSCT that contribute to lung injury.
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