Hypochlorite Detection by Fluorescent Sensors Bearing Long Alkyl Chains: The Role of Chain Length in Sensing Properties.

Three pyridinium derivatives bearing alkyl chains of different lengths (C1, C8, and C18) that show aggregation-enhanced emission were synthesized. These compounds can be used to detect ClO - ion as the reaction releases the fluorescent core with an increase in emission intensity and change in absorption wavelength. The lowest detection limit of TPA-Pyr-18C was 6.04 μM. The length of the alkyl chain and resulting lipophilicity allowed the targeting of different subcellular structures. TPA-Pyr-18C could be used for staining yolk lipids in zebrafish.