Morphofunctional Changes in Brain and Peripheral Blood in Adult and Aged Wistar Rats with AlCl 3 -Induced Neurodegeneration.
Alexandra Vladislavovna SentyabrevaEkaterina Alexandrovna MiroshnichenkoEkaterina Andreevna MelnikovaIvan Sergeevich TsvetkovAnna Mikhailovna KosyrevaPublished in: Biomedicines (2023)
compared to young animals, aged rats respond to aluminum exposure with a severe decline of most cells' function and irreversible neuronal loss. Regarding all reported data, neurodegeneration modelling and investigating of factors capable of accelerating or preventing it should be performed in experimental work on aged animals.
Keyphrases
- peripheral blood
- induced apoptosis
- diabetic rats
- cerebral ischemia
- white matter
- electronic health record
- drug induced
- early onset
- resting state
- big data
- oxidative stress
- machine learning
- blood brain barrier
- young adults
- deep learning
- functional connectivity
- cell death
- artificial intelligence
- subarachnoid hemorrhage
- brain injury
- childhood cancer