Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.

Jun LiJinshu XuHuihui JiangTing ZhangAarthi RamakrishnanLi ShenPin-Xian Xu

Published in: Journal of the American Society of Nephrology : JASN (2021)

Our results reveal an essential role for Brg1, its downstream pathways, and its interaction with Eya1-Six2 in mediating the fine balance among the self-renewal, differentiation, and survival of nephron progenitors.

Keyphrases

genome wide
gene expression
dna damage
air pollution
transcription factor
single cell
dna methylation
free survival
oxidative stress