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An empirical comparison of population genetic analyses using microsatellite and SNP data for a species of conservation concern.

Shawna J ZimmermanCameron L AldridgeSara J Oyler-McCance
Published in: BMC genomics (2020)
We demonstrate that SNPs have three main advantages over microsatellites: more precise estimates of population-level diversity, higher power to identify groups in clustering methods, and the ability to consider local adaptation. This study adds to a growing body of work comparing the use of SNPs and microsatellites to evaluate genetic diversity and differentiation for a species of conservation concern with relatively high population structure and using the most common method of obtaining SNP genotypes for non-model organisms.
Keyphrases
  • genetic diversity
  • genome wide
  • dna methylation
  • electronic health record
  • copy number
  • single cell
  • rna seq
  • big data
  • gram negative
  • multidrug resistant
  • artificial intelligence
  • high density