ImmunoPET of Ovarian and Pancreatic Cancer with AR9.6, a Novel MUC16-Targeted Therapeutic Antibody.

Sai Kiran SharmaKyeara N MackAlessandra PiersigilliJacob PouratKimberly J EdwardsOuti KeinänenMaria S JiaoHuiyong ZhaoBrandy WhiteCory L BrooksElisa De StanchinaMadi R MadiyalakanMichael A Hollingsworth Prakash Radhakrishnan Jason S Lewis Brian M Zeglis

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

The unique therapeutic mechanism of AR9.6 combined with its excellent in vivo tumor targeting makes it a highly promising theranostic agent. huAR9.6 is poised for clinical translation to impact the management of metastatic ovarian and pancreatic cancers.

Keyphrases

cancer therapy
squamous cell carcinoma
small cell lung cancer
photodynamic therapy
fluorescence imaging
young adults
childhood cancer