Role of TRPV1 receptor in inflammation and impairment of esophageal mucosal integrity in a murine model of nonerosive reflux disease.
R O SilvaR D BinganaT M A L SalesR L R MoreiraD V S CostaK M O SalesG A C BritoA A SantosMarcellus Henrique Loiola Ponte de SouzaP M G SoaresD SifrimM H L P SouzaPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
The TRPV1 receptor has a critical role in esophageal inflammation and mucosal barrier impairment in NERD mice, suggesting that TRPV1 might be a pharmacological target in patients with NERD.