Association of Dynamic Trajectories of Time-Series Data and Life-Threatening Mass Effect in Large Middle Cerebral Artery Stroke.
Charlene J OngQiuxi HuangIvy So Yeon KimJack PohlmannStefanos ChatzidakisBenjamin BrushYihan ZhangYili DuLeigh Ann MalingerEmelia J BenjaminJosée DupuisDavid M GreerStelios M SmirnakisLudovic TrinquartPublished in: Neurocritical care (2024)
Longitudinal profiling adjusted for confounders demonstrated that white blood cell count, temperature, and sodium levels appear to increase before radiographic and clinical indicators of space-occupying mass effect. These findings will inform the development of multivariable dynamic risk models to aid prediction of life-threatening, space-occupying mass effect.