Allergic bronchopulmonary mycosis in Schizophyllum commune with positive Aspergillus -specific IgE antibodies: A case report.
Hiroshi TakahashiMasamitsu HamakawaTadashi IshidaAkira WatanabePublished in: Respirology case reports (2024)
Schizophyllum commune is the third most common causative fungus of allergic bronchopulmonary mycosis(ABPM). Two-thirds of ABPM caused by S. commune can be positive for Aspergillus fumigatus -specific IgE, which can be difficult to diagnose. Our patient presented to our hospital with wet cough for 3 months and chest pain for 3 days. Blood tests showed IgE 1522 IU/mL, eosinophils 688/mm 3 , A. fumigatus -specific IgE 2.24 UA/mL, and chest computed tomography showed high-attenuation mucus. Bronchoscopy showed mucus plugs and speculum examination showed filamentous fungi, but various culture tests did not detect A. fumigatus , Asp f 1-specific IgE was negative, and S. commune was detected in the culture of bronchial washing. Since he was positive for S. commune -specific IgE and IgG, he diagnosed ABPM caused by S. commune . These findings demonstrate the importance of identifying the causative fungus in ABPM by detailed examination.