HBVsvp-Pulsed Dendritic Cell Immunotherapy Induces Th1 Polarization and Hepatitis B Virus-Specific Cytotoxic T Lymphocytes Production.

Mohamed M S FaragReda A SuefGhada M Al-ToukhyMohamed A SelimMostafa A ElbahnasawyNahla El SharkawySameera EzzatNashwa Abuel-Fetuh SheblMohamed T M Mansour

Published in: Infection and drug resistance (2020)

Overall, our data suggest that in vitro activation of MoDCs with HBVsvp overcomes the functionally impaired DCs and T cells in CHB patients offering a promising tool for therapeutic or vaccine-based approaches against HBV.

Keyphrases

hepatitis b virus
dendritic cells
end stage renal disease
liver failure
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
electronic health record
regulatory t cells
patient reported outcomes
big data
machine learning
artificial intelligence
deep learning