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Effects of aging on the histology and biochemistry of rat tendon healing.

Fan LaiHong TangJingjing WangKang LuXuting BianYunjiao WangYouxing ShiYupeng GuoGang HeMei ZhouXuan ZhangBinghua ZhouJiqiang ZhangWan ChenKanglai Tang
Published in: BMC musculoskeletal disorders (2021)
Our findings indicate that tendon healing is impaired in aged rats and is characterized by a significantly lower histological score, decreased collagen synthesis and more adipocyte accumulation in patellar tendon after repair.
Keyphrases
  • anterior cruciate ligament reconstruction
  • rotator cuff
  • adipose tissue
  • insulin resistance
  • oxidative stress
  • total knee arthroplasty
  • metabolic syndrome
  • tissue engineering