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Evaluation of clonality from multiple anatomic sites in canine epitheliotropic T cell lymphoma.

M Kelly KeatingWayne S RosenkrantzStefan M KellerPeter F Moore
Published in: Veterinary dermatology (2022)
These findings show that canine eCTCL lesions in multiple locations harbour the same neoplastic clone, neoplastic lymphocytes do not remain fixed to the skin and instead can circulate via blood, differing clones can be identified in skin versus blood, and circulating neoplastic cells can be detected without lymphocytosis.
Keyphrases
  • induced apoptosis
  • soft tissue
  • wound healing
  • peripheral blood
  • endoplasmic reticulum stress
  • oxidative stress
  • signaling pathway
  • cell proliferation