Pharmacodynamics of rituximab on B lymphocytes in paediatric patients with autoimmune diseases.

Shan PanHuixin YuAyesha SurtiIek ChengStephen D MarksPaul A BroganDespina EleftheriouJoseph F Standing

Published in: British journal of clinical pharmacology (2019)

Rituximab pharmacodynamics (PD) in paediatric autoimmune diseases has been described. Compared with rituximab alone, the additional effect of methotrexate or cyclophosphamide was statistically significant but small.

Keyphrases

diffuse large b cell lymphoma
chronic lymphocytic leukemia
hodgkin lymphoma
intensive care unit
high dose
emergency department
low dose