Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging.

Nishanth D TirukotiLiat AvramReut MashiachHyla Allouche-ArnonAmnon Bar-Shir

Published in: Chemical communications (Cambridge, England) (2022)

An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed to sense Zn 2+ with 19 F-iCEST MRI, in the future.

Keyphrases

contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
cancer therapy
high resolution
computed tomography
heavy metals
magnetic resonance
wastewater treatment
positron emission tomography
current status
photodynamic therapy
water soluble