High-fat diet promotes hypothalamic inflammation in animal models: a systematic review.
Lucimeire Santana Dos SantosGabriele Dos Santos CordeiroRhowena Jane Barbosa de MatosGabriela Dos Santos PerezRafael T SilvaGilson Teles BoaventuraJairza Maria Barreto MedeirosPublished in: Nutrition reviews (2021)
The exposure of rodents to high-fat diets promoted an increase in levels of several pro-inflammatory cytokines and other proteins involved in the inflammatory process in the hypothalamus. This process was associated with increased glial cell activity.