Humanin inhibits lymphatic endothelial cells dysfunction to alleviate myocardial infarction-reperfusion injury via BNIP3-mediated mitophagy.

Lu ChenXiaohua YangKai WangLina GuoCao Zou

Published in: Free radical research (2024)

In conclusion, HN alleviates myocardial infarction-reperfusion injury by inhibiting lymphatic endothelial cells dysfunction, primarily through BNIP3-mediated mitophagy.

Keyphrases

endothelial cells
cerebral ischemia
acute myocardial infarction
lymph node
heart failure
left ventricular
oxidative stress
high glucose
acute ischemic stroke
signaling pathway
vascular endothelial growth factor
mouse model
percutaneous coronary intervention
blood brain barrier
acute coronary syndrome