Overlap between COPD genetic association results and transcriptional quantitative trait loci.

Aabida SaferaliWonji KimRobert P Chasenull nullChris VollmersEdwin K SilvermanMichael H ChoPeter J CastaldiCraig P Hersh

Published in: medRxiv : the preprint server for health sciences (2024)

A total of 38 COPD GWAS loci contain evidence of sQTLs, suggesting that analysis of sQTLs in whole blood and lung tissue can provide novel insights into disease mechanisms.

Keyphrases

genome wide
chronic obstructive pulmonary disease
genome wide association study
lung function
dna methylation
copy number
genome wide association
gene expression
transcription factor
high resolution
air pollution
mass spectrometry
heat shock