Tumor Heterogeneity in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer Assessed by CT Texture Analysis: Association with Survival after Trastuzumab Treatment.
Sung Hyun YoonYoung Hoon KimYoon Jin LeeJihoon ParkJin Won KimHye Seung LeeBohyoung KimPublished in: PloS one (2016)
Heterogeneous texture features on CT images were associated with better survival in patients with HER2-positive advanced gastric cancer who received trastuzumab-based treatment. Therefore, texture analysis shows potential to be a clinically useful imaging biomarker providing additional prognostic information for patient selection.
Keyphrases
- epidermal growth factor receptor
- contrast enhanced
- tyrosine kinase
- computed tomography
- advanced non small cell lung cancer
- endothelial cells
- high resolution
- neoadjuvant chemotherapy
- image quality
- magnetic resonance imaging
- magnetic resonance
- combination therapy
- dual energy
- squamous cell carcinoma
- radiation therapy
- lymph node
- risk assessment
- replacement therapy
- health information
- mass spectrometry
- photodynamic therapy
- locally advanced
- metastatic breast cancer
- pet ct
- smoking cessation