MFAP4-Deficiency Aggravates Age-Induced Changes in Resistance Artery Structure, While Ameliorating Hypertension.
Kimmie B ChristensenŞeyda ÜnsalMorten Frendø EbbesenLine HemstraAnders SchlosserKristoffer RosenstandPernille B L HansenBoye L JensenMaria BloksgaardUlf SimonsenGrith Lykke SorensenPublished in: Hypertension (Dallas, Tex. : 1979) (2024)
MFAP4-deficiency reduces the elastin/collagen ratio in the aging resistance artery without affecting arterial stiffness. In contrast, MFAP4-deficiency reduces the stiffness of resistance arteries and ameliorates Ang II-induced hypertension.