Activated but impaired IFN-γ production of mucosal-associated invariant T cells in patients with hepatocellular carcinoma.

Wenyong HuangDongmei YeWenjing HeXiaoshun HeXiaomin ShiYifang Gao

Published in: Journal for immunotherapy of cancer (2022)

Our study showed that alterations in MAIT cells are associated with HCC. The distinct activity and function of MAIT cells in the peripheral blood and liver of patients with HCC might suggest a potential role of these cells in disease pathogenesis.

Keyphrases

induced apoptosis
cell cycle arrest
peripheral blood
endoplasmic reticulum stress
risk assessment
cell proliferation
climate change