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Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice.

Alba Sanz-GonzálezIrene Cózar-CastellanoChristophe BrocaJulia SabatierGerardo A AcostaMiriam RoyoCarla Hernándo-MuñozTomás TorrobaGermán PerdomoBeatriz Merino
Published in: Diabetes, obesity & metabolism (2023)
We conclude that sPIF is a promising secretagogue for the treatment of T2D.
Keyphrases
  • type diabetes
  • glycemic control
  • combination therapy
  • metabolic syndrome
  • insulin resistance