Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice.
Alba Sanz-GonzálezIrene Cózar-CastellanoChristophe BrocaJulia SabatierGerardo A AcostaMiriam RoyoCarla Hernándo-MuñozTomás TorrobaGermán PerdomoBeatriz MerinoPublished in: Diabetes, obesity & metabolism (2023)
We conclude that sPIF is a promising secretagogue for the treatment of T2D.