Detrimental pro-senescence effects of vitamin D on lung fibrosis.

Trinidad GuijarroEsmeralda Magro-LopezJoana MansoRicardo Garcia-MartinezMaria Jesus Fernandez-AceñeroIsabel ListeAlberto Zambrano

Published in: Molecular medicine (Cambridge, Mass.) (2018)

The detrimental effects of vitamin D in the presence of a DNA damaging agent might preclude its use as an antifibrogenic agent for pulmonary fibrosis characterized by DNA damage occurrence and cellular senescence.

Keyphrases

dna damage
pulmonary fibrosis
dna repair
oxidative stress
endothelial cells
risk assessment
stress induced
liver fibrosis