Serial quantitation of plasma microbial cell-free DNA before and after diagnosis of pulmonary invasive mold infections in hematopoietic cell transplant recipients.

Madeleine R HeldmanAsim A AhmedWinnie LiuAlythia VoJacob Keane-CandibTerry Stevens-AyersMichael BoeckhTimothy A BlauwkampCynthia E FisherJoshua A Hill

Published in: The Journal of infectious diseases (2023)

Plasma mcfDNA-Seq can identify pathogenic molds up to three weeks before clinical diagnosis of pulmonary IMI. Plasma mcfDNA concentrations may correlate with extrapulmonary spread and mortality in non-Aspergillus IMI.

Keyphrases

pulmonary hypertension
single cell
ms ms
bone marrow
microbial community
type diabetes
rna seq
gene expression
liquid chromatography tandem mass spectrometry
coronary artery disease
gestational age
preterm birth