Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice.

Arvin Iracheta-VellveJan PetrasekBenedek GyogyosiShashi BalaTimea CsakKaren KodysGyongyi Szabo

Published in: Liver international : official journal of the International Association for the Study of the Liver (2017)

Our novel findings suggest that IL-1 drives sustained liver inflammation and impaired hepatocyte regeneration even after cessation of ethanol exposure.

Keyphrases

liver injury
drug induced
stem cells
oxidative stress
wound healing
high fat diet induced
type diabetes
skeletal muscle