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Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model.

Hamed ZareHamid BakheradArman Nasr EsfahaniMohamad NorouziHossein AghamollaeiSeyed Latif Mousavi GargariFatemeh MahmoodiMahdi AliomraniWalead Ebrahimizadeh
Published in: BioImpacts : BI (2023)
cGRP78 vaccines generated potent immunotherapeutic effects in a breast cancer mouse model. This novel strategy of targeting the GRP78 protein can promote the development of cancer vaccines and immunotherapies for breast cancer malignancies.
Keyphrases
  • mouse model
  • endoplasmic reticulum stress
  • papillary thyroid
  • cell surface
  • childhood cancer
  • cancer therapy
  • squamous cell carcinoma
  • amino acid
  • lymph node metastasis
  • anti inflammatory
  • breast cancer risk
  • cell free