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Directional Deep Brain Stimulation for Parkinson's Disease: Results of an International Crossover Study With Randomized, Double-Blind Primary Endpoint.

Alfons SchnitzlerPablo MirMatthew A BrodskyLeonard VerhagenSergiu GroppaRamiro AlvarezAndrew Howard EvansMarta BlázquezSean J NagelJulie Georgia PilitsisMonika Pötter-NergerWinona TseLeonardo AlmeidaNestor TomyczJoohi Jimenez-ShahedWitold LibionkaFatima CarrilloChristian J HartmannStefan Jun GroissMartin GlaserFlorence DefresneEdward KarstBinith CheeranJan Vespernull null
Published in: Neuromodulation : journal of the International Neuromodulation Society (2021)
Directional stimulation yielded a wider TW compared to omnidirectional stimulation and was preferred by blinded subjects and clinicians.
Keyphrases
  • deep brain stimulation
  • placebo controlled
  • double blind
  • parkinson disease
  • phase iii
  • obsessive compulsive disorder
  • clinical trial
  • phase ii
  • study protocol
  • open label
  • palliative care