Angiogenic content of microparticles in patients with diabetes and coronary artery disease predicts networks of endothelial dysfunction.
Isra MareiOmar ChidiacBinitha ThomasJennifer PasquierSoha DarghamAmal RobayMuneera VakayilMohammad JameeshChristopher TriggleArash RafiiAmin JayyousiJassim Al SuwaidiCharbel Abi KhalilPublished in: Cardiovascular diabetology (2022)
Our data showed that the release of apoptosis-induced EMPs is increased in diabetes, irrespective of CAD, ACS patients having the highest levels. The protein contents of MPs interact in networks that indicate vascular dysfunction.
Keyphrases
- coronary artery disease
- end stage renal disease
- oxidative stress
- ejection fraction
- newly diagnosed
- cardiovascular disease
- acute coronary syndrome
- chronic kidney disease
- diabetic rats
- percutaneous coronary intervention
- cell death
- high glucose
- peritoneal dialysis
- heart failure
- machine learning
- endothelial cells
- cell proliferation
- binding protein
- drug induced
- patient reported