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Gut Microbiome Features Associated with Liver Fibrosis in Hispanics, a Population at High Risk for Fatty Liver Disease.

Suet-Ying KwanJingjing JiaoAron JoonPeng WeiLauren E PettyJennifer E BelowCarrie R DanielXiaogang WuJianhua ZhangRobert R JenqP Andrew FutrealErnest T HawkJoseph B McCormickSusan P Fisher-HochLaura Beretta
Published in: Hepatology (Baltimore, Md.) (2021)
Hispanics with liver fibrosis display microbiome profiles and associated functional changes that may promote oxidative stress and a pro-inflammatory environment. These microbiome signatures, together with NCK2 polymorphisms, may have utility in risk modeling and disease prevention in this high-risk population.
Keyphrases
  • liver fibrosis
  • oxidative stress
  • dna damage
  • gene expression
  • signaling pathway
  • endoplasmic reticulum stress
  • heat shock
  • heat stress