A novel intra-ventricular assist device enhances cardiac performance in normal and acutely failing isolated porcine hearts.
Daniël I M van DortJos ThannhauserWim J MorshuisGuillaume Sc GeuzebroekDirk J DunckerPublished in: The International journal of artificial organs (2021)
IVMP-support improved mechanical efficiency under physiological conditions, as the marked increase in cardiac performance only resulted in a modest increase in oxygen consumption. Moreover, the IVMP rapidly restored cardiac performance under conditions of acute pump failure. These observations warrant further study, to evaluate the effects of IVMP-support in in vivo animal models of acute cardiac pump failure.