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TSLP promoting B cell proliferation and polarizing follicular helper T cell as a therapeutic target in IgG4-related disease.

Hui LuXunyao WuYu PengRuijie SunYuxue NieJingna LiMu WangYaping LuoLinyi PengYunyun FeiJiaxin ZhouWen ZhangXiaofeng Zeng
Published in: Journal of translational medicine (2022)
Elevated TSLP in IgG4-RD promoted B cells proliferation and polarized Tfh cells and might be served as a potential therapeutic target.
Keyphrases
  • cell proliferation
  • induced apoptosis
  • signaling pathway
  • cell cycle arrest
  • regulatory t cells
  • pi k akt
  • dendritic cells
  • cell cycle
  • oxidative stress
  • immune response