Acid-suppressive medication and incidence of chronic childhood immune-mediated diseases: A scoping review.
Joanna MadejTania AtanassovaSarah McGuireBarrie CohenMelissa WeidnerYingting ZhangDaniel B HortonPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2023)
In summary, prenatal or pediatric exposure to PPIs and/or H2RAs has frequently, but not exclusively, been associated with the development of asthma, other allergic diseases, and chronic gastrointestinal IMDs. However, concerns remain about confounding and other sources of bias. Prescribers and families should be aware of these possible risks of ASMs.