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Population pharmacokinetics of cefazolin in maternal and umbilical cord plasma, and simulated exposure in term neonates.

Omar ElkayalKarel AllegaertIsabel SprietAnne SmitsMarie-Christine SeghayeCorinne CharlierErwin Dreesen
Published in: The Journal of antimicrobial chemotherapy (2021)
PopPK simulations showed that standard pre-delivery maternal cefazolin dosing provided adequate target attainment up to the time of delivery.
Keyphrases
  • umbilical cord
  • mesenchymal stem cells
  • birth weight
  • gestational age
  • preterm infants
  • molecular dynamics
  • bone marrow
  • weight gain
  • monte carlo