HPMC improves protective effects of naringenin and isonicotinamide co-crystals against abdominal aortic aneurysm.

Xing ZhangAnyi WangXiaotong YangYunxia WangQinyu WangRui HuGulinigaer AnwaierChang DiRong QiYanbin Huang

Published in: Cardiovascular drugs and therapy (2021)

NGN-INT significantly improved the absorption and aortic protective effects of NGN. The supersaturation-prolonging effect of HPMC further enhanced bioavailability and anti-AAA effects of NGN-INT.

Keyphrases

abdominal aortic aneurysm
aortic valve
pulmonary artery
left ventricular
room temperature
coronary artery
pulmonary arterial hypertension